Gastrointestinal diseases (GIDs) involve various benign and malignant pathologies of the digestive tract, as well as the liver, biliary tract, and pancreas [1]. The common clinical symptoms of GIDs are as follows: abdominal pain, heartburn, nausea, vomiting, bloating, diarrhea, constipation, and gastrointestinal bleeding [1]. Gastrointestinal diseases (GIDs) involve various benign and malignant pathologies of the digestive tract, as well as the liver, biliary tract, and pancreas [1]. The common clinical symptoms of GIDs are as follows: abdominal pain, heartburn, nausea, vomiting, bloating, diarrhea, constipation, and gastrointestinal bleeding [1]. This paper will provide an overview of the current knowledge of digestive enzyme supplementation in gastrointestinal diseases and include also publications with animals and in vitro studies . We did a non-systematic but thorough review of the available literature.
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